' 
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Total Carbohydrate
<1g
<1%†
Calcium (from calcium magnesium phytate)
131 mg
10%
Phosphorus (from calcium magnesium phytate)
192 mg
15%
Magnesium (from calcium magnesium phytate)
40 mg
10%
IP-6 (inositol hexaphosphate) (from calcium magnesium phytate)
800 mg
**
Inositol
220 mg
**
Maitake Mushroom Extract standardized to 30% pure D-fraction (9 mg)
30 mg
**
Cat's Claw Extract (bark) standardized to 4% alkaloids (0.4 mg)
10 mg
**
Top Medical Research Studies
7
Cat's claw shows potential benefits
Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis.
Moderate relevance to treatment effectiveness
We explored the effectiveness of cat's claw in managing autoimmune disorders, specifically osteoarthritis (OA) and rheumatoid arthritis (RA). Our review included various studies, focusing on its potential as a dietary supplement to reduce inflammation and oxidative stress associated with these conditions.
From the research, we found three studies that support the use of cat's claw, whether alone or in combination with other treatments, for patients suffering from OA. However, while some evidence exists, we noted that the effectiveness of cat's claw for RA isn't as robust.
It's important to recognize, though, that the full impact of cat's claw on autoimmune disorders needs more thorough research. Many factors, including varying responses to treatment, call for caution in making solid recommendations based solely on the existing studies.
Overall, while there’s promise in using cat's claw for managing autoimmune conditions, we should approach it with realistic expectations and an understanding that further investigation is necessary before solid conclusions can be drawn.
From the research, we found three studies that support the use of cat's claw, whether alone or in combination with other treatments, for patients suffering from OA. However, while some evidence exists, we noted that the effectiveness of cat's claw for RA isn't as robust.
It's important to recognize, though, that the full impact of cat's claw on autoimmune disorders needs more thorough research. Many factors, including varying responses to treatment, call for caution in making solid recommendations based solely on the existing studies.
Overall, while there’s promise in using cat's claw for managing autoimmune conditions, we should approach it with realistic expectations and an understanding that further investigation is necessary before solid conclusions can be drawn.
Read More
8
Myo-inositol enhances vitamin D effects
The impact of vitamin D on thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in myo-inositol-treated and myo-inositol-naïve women with autoimmune thyroiditis: A pilot study.
Impact of combined treatments
Our study aimed to explore the impact of myo-inositol treatment on thyroid autoimmunity in women with autoimmune thyroiditis. We included groups of women who had been on myo-inositol for a while and those who hadn’t. For six months, we observed how vitamin D supplementation interacted with myo-inositol in affecting thyroid health and immune responses.
We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.
Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.
Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
Read More
4
Myo-inositol shows no benefit
Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis.
Inositol's isolated effects unclear
We aimed to understand the impact of Myo-inositol on thyroid autoantibody levels in patients with Hashimoto's thyroiditis (HT). Our analysis included data from a systematic review of several case-control studies that explored various dietary supplements, particularly focusing on inositol's effectiveness.
Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).
This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).
This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Read More
Most Useful Reviews
8.8
Supports recovery
I have been taking Cell Forte MAX3 for a few months after being diagnosed with an autoimmune disorder and starting chemotherapy and immunotherapy. I feel that MAX3 has helped keep my body fit during this process. The product seems to be of good quality, and I believe it has benefitted me alongside a balanced diet. I am on my second batch and will reorder more.
Read More
8.8
Prevents illness
I think it's a great product. I have finished one bottle and will reorder it. I take it for prevention, and despite my three children suffering from the flu, I didn’t catch it from them.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6
- All Researches
8
Myo's impact on autoimmune thyroiditis
Myoinositol in Autoimmune Thyroiditis.
Combination therapy assessed; limited isolation
Our exploration focused on how Myoinositol, often known as Myo, impacts autoimmune disorders, particularly autoimmune thyroiditis. We learned that Myo plays a crucial role in the body's thyroid function by aiding in the production of thyroid hormones and regulating iodine, which is essential in this process.
Interestingly, when Myo was combined with Selenium in treatment, patients with subclinical hypothyroidism showed significant decreases in thyroid-stimulating hormone (TSH) levels. Additionally, levels of antithyroid autoantibodies also dropped, which is promising for those battling autoimmune thyroid issues.
However, it is important to note that the study did not exclusively isolate the effect of Myoinositol, as the results were observed in conjunction with Selenium. Therefore, while the findings are encouraging, we cannot definitively claim that Myo alone yields the same benefits in managing autoimmune disorders.
Interestingly, when Myo was combined with Selenium in treatment, patients with subclinical hypothyroidism showed significant decreases in thyroid-stimulating hormone (TSH) levels. Additionally, levels of antithyroid autoantibodies also dropped, which is promising for those battling autoimmune thyroid issues.
However, it is important to note that the study did not exclusively isolate the effect of Myoinositol, as the results were observed in conjunction with Selenium. Therefore, while the findings are encouraging, we cannot definitively claim that Myo alone yields the same benefits in managing autoimmune disorders.
Read More
8
Myo-inositol enhances vitamin D effects
The impact of vitamin D on thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in myo-inositol-treated and myo-inositol-naïve women with autoimmune thyroiditis: A pilot study.
Impact of combined treatments
Our study aimed to explore the impact of myo-inositol treatment on thyroid autoimmunity in women with autoimmune thyroiditis. We included groups of women who had been on myo-inositol for a while and those who hadn’t. For six months, we observed how vitamin D supplementation interacted with myo-inositol in affecting thyroid health and immune responses.
We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.
Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.
Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
Read More
7
Cat's claw shows potential benefits
Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis.
Moderate relevance to treatment effectiveness
We explored the effectiveness of cat's claw in managing autoimmune disorders, specifically osteoarthritis (OA) and rheumatoid arthritis (RA). Our review included various studies, focusing on its potential as a dietary supplement to reduce inflammation and oxidative stress associated with these conditions.
From the research, we found three studies that support the use of cat's claw, whether alone or in combination with other treatments, for patients suffering from OA. However, while some evidence exists, we noted that the effectiveness of cat's claw for RA isn't as robust.
It's important to recognize, though, that the full impact of cat's claw on autoimmune disorders needs more thorough research. Many factors, including varying responses to treatment, call for caution in making solid recommendations based solely on the existing studies.
Overall, while there’s promise in using cat's claw for managing autoimmune conditions, we should approach it with realistic expectations and an understanding that further investigation is necessary before solid conclusions can be drawn.
From the research, we found three studies that support the use of cat's claw, whether alone or in combination with other treatments, for patients suffering from OA. However, while some evidence exists, we noted that the effectiveness of cat's claw for RA isn't as robust.
It's important to recognize, though, that the full impact of cat's claw on autoimmune disorders needs more thorough research. Many factors, including varying responses to treatment, call for caution in making solid recommendations based solely on the existing studies.
Overall, while there’s promise in using cat's claw for managing autoimmune conditions, we should approach it with realistic expectations and an understanding that further investigation is necessary before solid conclusions can be drawn.
Read More
7
Cat's claw shows modest RA benefits
Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of uncaria tomentosa for the treatment of rheumatoid arthritis.
Effect of concurrent medications noted
We engaged in an interesting exploration of how a plant extract from cat's claw, specifically the pentacyclic chemotype of Uncaria tomentosa, might help those suffering from rheumatoid arthritis (RA). Our study involved forty patients who were already on medications like sulfasalazine or hydroxychloroquine, which allowed us to evaluate the extract's effectiveness in addition to these existing treatments.
Over the course of 52 weeks, we structured the study into two phases. The first 24 weeks were double-blind and placebo-controlled, meaning neither the patients nor the researchers knew who was receiving the actual cat's claw extract and who was getting a placebo. This approach adds credibility to the findings. After the initial phase, all patients received the plant extract for another 28 weeks.
Notably, we found that after 24 weeks of treatment with the cat's claw extract, patients experienced a significantly larger reduction in painful joints compared to those taking the placebo. The results highlighted a 53.2% decrease in painful joints with the extract versus 24.1% with the placebo, a finding we felt was particularly promising. Even in the second phase, where patients received the extract after an initial placebo, there were marked improvements in tender and swollen joints.
Importantly, throughout the study, we observed only minor side effects, suggesting that cat's claw is relatively safe for this patient population. Our findings indicate that this plant extract could be a modest but helpful addition for patients dealing with active rheumatoid arthritis, particularly for those who are already on other treatments.
Over the course of 52 weeks, we structured the study into two phases. The first 24 weeks were double-blind and placebo-controlled, meaning neither the patients nor the researchers knew who was receiving the actual cat's claw extract and who was getting a placebo. This approach adds credibility to the findings. After the initial phase, all patients received the plant extract for another 28 weeks.
Notably, we found that after 24 weeks of treatment with the cat's claw extract, patients experienced a significantly larger reduction in painful joints compared to those taking the placebo. The results highlighted a 53.2% decrease in painful joints with the extract versus 24.1% with the placebo, a finding we felt was particularly promising. Even in the second phase, where patients received the extract after an initial placebo, there were marked improvements in tender and swollen joints.
Importantly, throughout the study, we observed only minor side effects, suggesting that cat's claw is relatively safe for this patient population. Our findings indicate that this plant extract could be a modest but helpful addition for patients dealing with active rheumatoid arthritis, particularly for those who are already on other treatments.
Read More
4
Myo-inositol shows no benefit
Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis.
Inositol's isolated effects unclear
We aimed to understand the impact of Myo-inositol on thyroid autoantibody levels in patients with Hashimoto's thyroiditis (HT). Our analysis included data from a systematic review of several case-control studies that explored various dietary supplements, particularly focusing on inositol's effectiveness.
Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).
This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).
This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Supports recovery
I have been taking Cell Forte MAX3 for a few months after being diagnosed with an autoimmune disorder and starting chemotherapy and immunotherapy. I feel that MAX3 has helped keep my body fit during this process. The product seems to be of good quality, and I believe it has benefitted me alongside a balanced diet. I am on my second batch and will reorder more.
Read More
8.8
Prevents illness
I think it's a great product. I have finished one bottle and will reorder it. I take it for prevention, and despite my three children suffering from the flu, I didn’t catch it from them.
